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Lumbar spineNICE alignedCSP aligned6 min read

How do you spot inflammatory back pain among mechanical presentations?

Recognising features of axial spondyloarthritis (including ankylosing spondylitis) and when to refer to rheumatology.

Subjective triage

  • Back pain starting before age 45 and lasting longer than three months.
  • Morning stiffness lasting more than 30 minutes that improves with movement.
  • Night pain in the second half of the night, waking the patient.
  • Improvement with exercise but not with rest; alternating buttock pain.
  • Associated features: uveitis, psoriasis, inflammatory bowel disease, family history, or good response to anti-inflammatories.

Differential dilemma: vs lumbar facet-mediated pain

FeatureAxial spondyloarthritis vs mechanical back painLumbar facet-mediated pain
Morning stiffnessOften longer than 30 minutesUsually brief, easing within minutes
Response to activityImproves with exerciseAggravated by sustained extension or rotation
Night painWakes in the second half of the nightMainly positional discomfort
Wider featuresEye, skin, gut or family history linksNone

Red flags: recognise, screen, refer

Recognise

  • Unexplained weight loss, fever or night sweats
  • History of cancer
  • Thoracic pain with systemic illness
  • Severe unremitting night pain

Screen

Ask systematically about inflammatory features and extra-articular conditions; these are often missed for years.

Refer

Suspected axial spondyloarthritis should be referred to rheumatology for assessment. Serious pathology red flags follow urgent pathways.

The clinical reasoning chain

  1. 1

    History

    28-year-old with 6 months of low back pain, an hour of morning stiffness, better after exercise.

  2. 2

    Pattern

    Several inflammatory back pain features cluster together.

  3. 3

    Objective finding

    Reduced spinal mobility; mechanical tests do not explain the pattern.

  4. 4

    Diagnostic decision

    Possible axial spondyloarthritis: refer to rheumatology while keeping the patient active.

Quick reference FAQ

Is a normal X-ray reassuring for axial spondyloarthritis?

No. Early disease may not show on X-ray. Diagnosis is made by rheumatology using clinical features, blood tests and imaging such as MRI.

Should physiotherapists keep treating while awaiting referral?

Yes. Exercise and staying active are central to management, alongside medical care.

Why is the delay to diagnosis so long?

Symptoms are often attributed to mechanical back pain. Asking about inflammatory features in every young adult with persistent back pain helps.

More guides

Practise this real-world case in the Clinical Reasoning Lab